Dextromethorphan EP Impurity D HBr CAS 1453167-99-1(Free Base)

Description

Compared with other compounds in its class, the molecular weight of 352.32 g/mol gives Dextromethorphan EP Impurity D HBr distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies Dextromethorphan EP Impurity D HBr (CAS 1453167-99-1(Free Base)), a pharmacopoeial impurity reference standard (molecular formula C18H25NOHBr, MW 352.32 g/mol) used for the identification and quantification of trace impurities in APIs.

Based on its molecular formula C18H25NOHBr, Dextromethorphan EP Impurity D HBr contains a steroid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 352.32 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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